Antimicrobial Activity of Polyalthia longifolia (Sonn.) Thw. var. Pendula Leaf Extracts Against 91 Clinically Important Pathogenic Microbial Strains
نویسندگان
چکیده
The methanol, acetone and 1,4-dioxan fractions of leaves of Polyalthia longifolia (Sonn.) Thw. were evaluated for antibacterial and antifungal activity. 91 clinically important strains were used for the study which were both clinical isolates as well as identified strains. Piperacillin and gentamicin were used as standards for antibacterial assay, while nystatin and flucanazole were used as standards for antifungal assay. The antibacterial activity was more pronounced against gram positive bacterial and fungal strains. Poor activity was shown against gram negative bacterial strains studied.
منابع مشابه
Antimicrobial Activity of Terminalia catappa L. Leaf Extracts against Some Clinically Important Pathogenic Microbial Strains
Objective: The present study was undertaken to evaluate in-vitro antimicrobial activity of methanol, acetone and N, N-dimethylformamide extracts from leaf of Terminalia catappa L. (Combretaceae). Methods: In vitro antimicrobial activity of all the extracts was done by agar disc diffusion assay. 91 clinically important strains were used for the study, which were both clinical isolates as well as...
متن کاملThree new clerodane diterpenes from Polyalthia longifolia var. pendula.
Three new clerodane diterpenes, (4→2)-abeo-cleroda-2,13E-dien-2,14-dioic acid (1), (4→2)-abeo-2,13-diformyl-cleroda-2,13E-dien-14-oic acid (2), and 16(R&S)- methoxycleroda-4(18),13-dien-15,16-olide (3), were isolated from the unripe fruit of Polyalthia longifolia var. pendula (Annonaceae) together with five known compounds (4-8). The structures of all isolates were determined by spectroscop...
متن کاملEvalution of anti-ulcer activity of Polyalthia longifolia (Sonn.) Thwaites in experimental animals
OBJECTIVE To evaluate the anti-ulcer activity of ethanol extract of leaves of Polyalthia longifolia (Sonn.) Thwaites. MATERIALS AND METHODS The ethanol extract of Polyalthia longifolia was investigated for its anti-ulcer activity against aspirin plus pylorous ligation induced gastric ulcer in rats, HCl -Ethanol induced ulcer in mice and water immersion stress induced ulcer in rats at 300 mg/k...
متن کاملPhytochemical Analysis and Antimicrobial Activity of Polyalthia Longifolia
Polyalthia longifolia is a lofty evergreen plant, native to India, commonly planted due to its effectiveness in alleviating noise pollution. The has been used in the traditional system of medicine for the treatment of fever, skin diseases, diabetics and hypertension. A number of biologically active compounds have been isolated from the plant. However, its antimicrobial activity has not been inv...
متن کاملAntioxidant Activity and Hepatoprotective Potential of Polyalthia longifolia and Cassia spectabilis Leaves against Paracetamol-Induced Liver Injury
In the present study, in vitro antioxidant, free radical scavenging capacity, and hepatoprotective activity of methanol extracts from Polyalthia longifolia and Cassia spectabilis were evaluated using established in vitro models such as ferric-reducing antioxidant power (FRAP), 2,2-diphenyl-1-picryl-hydrazyl (DPPH(•)), hydroxyl radical (OH(•)), nitric oxide radical (NO(•)) scavenging, metal chel...
متن کامل